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Gene Predicts Breast Cancer Prognosis
10:46PM Wednesday Apr 23 2008 by lilhurricane
By Steven Reinberg

WEDNESDAY, April 23 (HealthDay News) -- A protein that stops the spread of breast cancer tumors in mice can predict which malignancies might spread, a new study suggests.

The gene, called bromodomain protein (Brd4), when added to breast cancer cells in mice, produced a unique gene signature, which was also detected in human breast cancer patients.

"We have identified that this particular gene seems to be associated with outcomes in breast cancer," said lead researcher Kent W. Hunter, a senior investigator at the U.S. National Cancer Institute. "This gene may be something we want to investigate in more detail."

Understanding how the new gene functions may lead to a better understanding of what makes breast cancer metastasize, Hunter said. "This will help identify patients who will have a better or worse outcome," he added.

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