There comes a time in many a cell's life when it feels the need to reproduce. But before it can split into two, it must fashion a second set of genetic instructions to pass on to the new cell.

When Berkeley professor of biochemistry and molecular biology Mike Botchan first began studying chromosome copying, basic questions about the process remained unknown. He wanted to understand how and where DNA replication began. Over the past three decades, Botchan has been instrumental in piecing together the story of what he calls "the elaborate dance of replication."

»sciencematters.berkeley.edu/arch···ory3.php