Here are some links regarding the Human Proteome Folding 2 project:
HPF2 Home page at the Bonneua lab at NYU
HPF2 Status Report
WCG Information Page
In depth PDF about the project
In terms of cancer research much information can be found here - why HPF2 is important: disease relevance
A snippet:
quote:
Protein Set #2: human cancer biomarkers of unknown structure and function.
Collaborator: Leroy Hood, Nathan Price, Institute for Systems Biology, Seattle, »www.systemsbiology.org/
Multiple groups involved at the Institute for Systems Biology are currently involved in a coordinated effort to characterize biomarkers that can be used for early diagnosis and sub-classification of Human cancers. In particular specific efforts are underway in the Laboratory of Leroy Hood to find prostrate, bladder and ovarian cancer biomarkers. This effort coordinates proteomic, microarray, pathology, and bioinformatics efforts into a overall effort to determine reliable and readily assayable predictors that can be used as markers for diagnosis and selection between alternate therapeutic/intervention regimes. The Bonneau and the worldcommunity grid lab are involved in the functional annotation of putative proteins and proteins of unknown function found in these studies. To date several hundred putative biomarkers of unknown function have been prioritized, and are being processed along with the other sets of proteins described above, on the world community grid. Along with Nathan Price, at the ISB in Seattle, the Bonneau lab has been applying structure based annotaiton to elucidate the structure/function of putative biomarkers discovered using these genome-wide screens.
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by Dersgniw  edited by lilhurricane
last modified: 2008-08-29 22:21:26 |
